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 sort of friendship with that consistency, such that there is no adverse reaction. In other words, if we are eating fruits and vegetables as we have been doing for the last hundred thousand years, the immune system perceives this is something that is quite natural. It’s like a bacterial virus that we’ve evolved over hundreds of thousands of years. And we have several of these. Of course, we call them our ‘little friends’; they are very friendly bacteria and microorganisms that we’ve grown with, and in fact we’ve come to depend on them.The sudden change that occurred around the time of the industrial revolutiolet’s say mid-19th century—has meant that our lifestyle has changed dramatically so that we’re eating processed foods that haven’t evolved with us over those hundreds of thousands of years. We’ve become much, much less active as a result of technology. The stress levels have changed dramatically. Our sleep levels have changed because we’ve got lights and electronics and so on. As a result, the body has reacted—the immune system has reacted—in this low grade, systemic, metae New England Journal of Medicine titled "Obesity and Metabolic Syndrome in Children and Adolescents." The prevalence of metabolic syndrome has increased significantly over the last decade and a half, and the prevalence of type 2 diabetes and cardiovascular disease has followed it, particularly in the adolescent population. In this article, the authors point out that the prevalence of the metabolic syndrome is high among obese children and adolescents and increases with worsening obesity. Biomarkers of an increased risk of adverse cardiovascular outcomes are already present in these youngsters, indicating that as they move into their 20s and 30s, they are likely to be high users of medical services because they will have complications of type 2 diabetes and cardiovascular disease at a much younger age than dramatic relationship to chronic health problems, metabolic disturbances, and virtually every chronic, age-related disease: coronary artery disease, stroke, hypertensive-related disorders, renal failure, diabetes, cancer, osteoporosis, arthritis, and spinal compression fractures. In 2005, a landmark paper was published in The New England Journal of Medicine from a group of collaborative investigators. This paper suggested that, based upon morbidity and mortality trends that are occurring in our society right now, children born today may be the first in the history of the United States to have mean average  These are dramatic social changes that are creatingpressure on the healthcare system, and a tremendous amount of human potential could be lost.Why are we seeing this rise in obesity? Is it just because of a luxurious diet that is rich in calories? Or is it a combination of the calories, plus the way calories are constructed in processed food that is sending signals to our genes and creating a different energy economy? What about psychosocial-related issues, such as post-traumatic stress syndrome and